The RANBP17 Polyclonal Antibody (PACO05064) is a valuable tool for researchers studying RANBP17, a protein involved in cellular processes related to nucleocytoplasmic transport and mitotic spindle assembly. This antibody, produced using rabbits, has high reactivity with human samples and has been validated for use in Western blot applications.RANBP17 is known for its role in regulating the transport of proteins into and out of the cell nucleus, as well as its involvement in the organization of the mitotic spindle during cell division. Research on RANBP17 is crucial for understanding its impact on cellular functions and its potential as a target for therapeutic interventions in diseases such as cancer.
With its ability to specifically bind to the RANBP17 protein, this antibody enables precise detection and analysis of RANBP17 in various cell types, making it an essential tool for studies in cell biology and cancer research. By delving into the functions of RANBP17, researchers can gain valuable insights into cellular processes and potentially discover new targets for drug development.
Antibody Name:
RANBP17 Antibody (PACO05064)
Antibody SKU:
PACO05064
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the N-terminal region of human Ran BP-17.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RANBP17; Ran-binding protein 17
UniProt Protein Function:
RANBP17: May function as a nuclear transport receptor. Belongs to the exportin family.Protein type: Nuclear export; Nuclear importChromosomal Location of Human Ortholog: 5q34Cellular Component: cytoplasm; nuclear poreMolecular Function: nuclear export signal receptor activity; Ran GTPase bindingBiological Process: protein export from nucleus
UniProt Protein Details:
NCBI Summary:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
