The RANBP10 Polyclonal Antibody (CAB17742) is a valuable tool for research involving the RANBP10 protein, a member of the Ran-binding protein family that plays a role in nucleocytoplasmic transport and cell cycle progression. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications, allowing for precise detection and analysis of RANBP10 in various cell types.The RANBP10 protein is involved in the transport of proteins and RNA molecules across the nuclear membrane, making it essential for the proper functioning of cells.
Dysregulation of RANBP10 has been linked to diseases such as cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target for research and drug development.By utilizing the RANBP10 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of RANBP10 in normal and disease states, paving the way for advances in biomedicine and potential therapeutic interventions. Its high specificity and sensitivity make it an ideal tool for studies in molecular biology, cell biology, and cancer research.
Product Name:
RANBP10 Rabbit Polyclonal Antibody
SKU:
CAB17742
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 362-497 of human RANBP10 (NP_065901.1).
RAN is a small GTPase involved in the assembly of microtubules to form mitotic spindles. The protein encoded by this gene is a cytoplasmic guanine nucleotide exchange factor (GEF) that binds beta-tubulin and has GEF activity toward RAN. The encoded protein plays a role in the formation of noncentrosomal microtubules. In addition, this protein may be involved in the regulation of D(1) receptor signaling by protein kinase C delta and protein kinase C gamma. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57610
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RANBP10 Rabbit pAb (CAB17742) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
