The RANBP1 Polyclonal Antibody (CAB16422) is a valuable tool for researchers studying RANBP1, a protein involved in nucleocytoplasmic transport and mitotic spindle assembly. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the RANBP1 protein, it allows for the detection and analysis of RANBP1 in various cell types, making it ideal for investigations in cell biology and cancer research.
RANBP1 plays a crucial role in the transport of proteins and RNAs between the nucleus and cytoplasm, as well as in the regulation of cell division. Its involvement in these fundamental cellular processes highlights its importance in various physiological and pathological conditions, including cancer. By studying the function of RANBP1, researchers can gain valuable insights into the mechanisms underlying cell division and potentially identify new targets for the development of cancer therapies.
Product Name:
RANBP1 Rabbit Polyclonal Antibody
SKU:
CAB16422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RANBP1 (NP_002873.1).
This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5902
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RANBP1 Rabbit pAb (CAB16422) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
