RAMP3 Rabbit Polyclonal Antibody (CAB6715)
- SKU:
- CAB6715
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RAMP3 Rabbit Polyclonal Antibody |
SKU: | CAB6715 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human RAMP3 (NP_005847.1). |
Sequence: | METG ALRR PQLL PLLL LLCG GCPR AGGC NETG MLER LPLC GKAF ADMM GKVD VWKW CNLS EFIV YYES FTNC TEME ANVV GCYW PNPL AQGF ITGI HRQF FSNC TVDR VHLE DPPD EV |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:10 - 1:100 |
Synonyms: | RAMP3 |
Positive Sample: | MCF7,SW620,Mouse brain,Mouse skin,Mouse kidney,Mouse heart,Mouse eye,Rat brain,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Membrane, Single-pass type I membrane protein. |
Calculated MW: | 17kDa |
Observed MW: | 40kDa |
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Purification Method: | Affinity purification |
Gene ID: | 10268 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |