The RalGDS Polyclonal Antibody (CAB17963) is a valuable tool for researchers studying RalGDS, a protein involved in cell signaling pathways and cancer progression. This antibody, raised in rabbits, is highly specific for RalGDS and is suitable for use in various applications, including Western blotting and immunohistochemistry.RalGDS is a guanine nucleotide exchange factor that activates the small GTPase Ral, leading to downstream signaling events that regulate cell proliferation, migration, and survival.
Dysregulation of RalGDS signaling has been implicated in various cancers, making it a promising therapeutic target for cancer treatment.By using the RalGDS Polyclonal Antibody, researchers can accurately detect and analyze RalGDS expression in different cell types and tissues, providing valuable insights into the role of RalGDS in cancer development and progression. This antibody is a valuable tool for advancing research in cancer biology and identifying potential targets for anti-cancer therapies.
Product Name:
RALGDS Rabbit Polyclonal Antibody
SKU:
CAB17963
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 771-902 of human RALGDS (NP_001258705).
Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
Purification Method:
Affinity purification
Gene ID:
5900
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RALGDS Rabbit pAb (CAB17963) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
