RAD9A Rabbit Polyclonal Antibody (CAB1890)
- SKU:
- CAB1890
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RAD9A Rabbit Polyclonal Antibody |
SKU: | CAB1890 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1). |
Sequence: | ALAE VTLG IGRG RRVI LRSY HEEE ADST AKAM VTEM CLGE EDFQ QLQA QEGV AITF CLKE FRGL LSFA ESAN LNLS IHFD APGR PAIF TIKD SLLD GHFV LATL SDTD SHSQ DLGS PERH QPVP QLQA HSTP HPDD FAND DIDS YMIA METT IGNE GSRV LPSI SLSP GPQP PKSP GPHS EEED EAEP STVP GTPP PKKF RSLF FGSI LAPV RSPQ GPSP VLAE DSEG EG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | RAD9; RAD9A |
Positive Sample: | BT-474,22Rv1,HepG2,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 43kDa |
Observed MW: | 60kDa |
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5883 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |