The RAD9A Polyclonal Antibody (CAB1890) is a valuable tool for researchers studying RAD9A, a protein involved in DNA damage response and cell cycle regulation. This antibody, raised in rabbits, is highly specific and reacts with human samples, making it ideal for Western blot applications. By binding to RAD9A, this antibody allows for the detection and analysis of RAD9A levels in various cell types, providing valuable insights into its role in DNA repair mechanisms and cell division processes.RAD9A, a member of the RAD9 checkpoint protein family, functions in DNA repair pathways to maintain genomic stability and prevent the accumulation of mutations.
Dysregulation of RAD9A has been implicated in cancer development and other diseases characterized by genomic instability. Therefore, understanding the function and regulation of RAD9A is essential for advancing research in cancer biology and personalized medicine strategies.Overall, the RAD9A Polyclonal Antibody (CAB1890) is a high-quality reagent that can enhance the study of RAD9A in various research areas, including cancer biology, DNA damage response, and cell cycle control. Its specificity and sensitivity make it a reliable tool for investigating the role of RAD9A in disease development and progression.
Product Name:
RAD9A Rabbit Polyclonal Antibody
SKU:
CAB1890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 162-391 of human RAD9A (NP_004575.1).
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5883
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAD9A Rabbit pAb (CAB1890) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
