Rad52 Rabbit Monoclonal Antibody (CAB5186)
- SKU:
- CAB5186
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Rad52 Rabbit Monoclonal Antibody |
SKU: | CAB5186 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 319-418 of human Rad52 (P43351). |
Sequence: | QELI KTLE DNSE KWAV TPDA GDGV VKPS SRAD PAQT SDTL ALNN QMVT QNRT PHSV CHQK PQAK SGSW DLQT YSAD QRTT GNWE SHRK SQDM KKRK YDPS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RAD52; DNA repair protein RAD52 homolog; Rad52 |
Positive Sample: | HeLa,293T,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 13kDa/15kDa/25kDa/46kDa |
Observed MW: | 50kDa |
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Purification Method: | Affinity purification |
Gene ID: | 5893 |
Clone Number: | ARC1183 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |