RAD51C Rabbit Polyclonal Antibody (CAB12487)
- SKU:
- CAB12487
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RAD51C Rabbit Polyclonal Antibody |
SKU: | CAB12487 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_002867.1). |
Sequence: | MRGK TFRF EMQR DLVS FPLS PAVR VKLV SAGF QTAE ELLE VKPS ELSK EVGI SKAE ALET LQII RREC LTNK PRYA GTSE SHKK CTAL ELLE QEHT QGFI ITFC SALD DILG GGVP LMKT TEIC GAPG VGKT QLW |
Tested Applications: | IF/ICC ELISA |
Recommended Dilution: | IF/ICC,1:50 - 1:100 |
Synonyms: | FANCO; R51H3; BROVCA3; RAD51L2; RAD51C |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, perinuclear region. |
Calculated MW: | 42kDa |
This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5889 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |