RAD51B Rabbit Polyclonal Antibody (CAB6962)
- SKU:
- CAB6962
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | RAD51B Rabbit Polyclonal Antibody |
SKU: | CAB6962 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human RAD51B (NP_598193.2). |
Sequence: | MGSK KLKR VGLS QELC DRLS RHQI LTCQ DFLC LSPL ELMK VTGL SYRG VHEL LCMV SRAC APKM QTAY GIKA QRSA DFSP AFLS TTLS ALDE ALHG GVAC GSLT EITG PPGC GKTQ FCIM MSIL ATLP TNMG GLEG AVVY IDTE SAFS AERL VEIA ESRF PRYF NTEE KLLL TSSK VHLY RELT CDEV LQRI ESLE EEII SKGI KLVI LDSV ASVV RKEF DAQL QGNL KERN KFLA REAS SLKY LAEE FSIP VILT NQIT THLS GALA SQAD LVSP ADDL SLSE GTSG SSCV IAAL GNTW SHSV NTRL ILQY LDSE RRQI LIAK SPLA PFTS FVYT IKEE GLVL QETT FCSV TQAE LNWA PEIL PPQP PEQL GLQM CHHT QLIF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | REC2; R51H2; RAD51L1; RAD51B |
Positive Sample: | Mouse kidney,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
Purification Method: | Affinity purification |
Gene ID: | 5890 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |