The Rad23A Rabbit Monoclonal Antibody (CAB5147) is a cutting-edge tool for researchers studying Rad23A, a protein involved in DNA repair and proteasomal degradation pathways. This antibody, generated using rabbit monoclonal technology, offers high specificity and sensitivity for detecting Rad23A in human samples, making it an excellent choice for Western blot and immunohistochemistry applications.Rad23A is a multifunctional protein that plays a crucial role in maintaining genomic stability and cellular homeostasis by facilitating DNA damage recognition and removal of misfolded proteins. Dysregulation of Rad23A has been linked to various human diseases, including cancer and neurodegenerative disorders.
By targeting Rad23A, researchers can gain insights into the molecular mechanisms underlying these conditions and develop potential therapeutic strategies.The Rad23A Rabbit Monoclonal Antibody (CAB5147) is a valuable research tool for investigating the function of Rad23A in cellular processes and disease pathogenesis. Its superior performance and reliability make it an essential reagent for scientists exploring the intricate roles of Rad23A in DNA repair, protein quality control, and beyond.
Product Name:
Rad23A Rabbit Monoclonal Antibody
SKU:
CAB5147
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Rad23A (P54725).
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
Purification Method:
Affinity purification
Gene ID:
5886
Clone Number:
ARC1271
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Rad23A Rabbit mAb (CAB5147) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
