The RAD23A Polyclonal Antibody is a valuable tool for researchers studying RAD23A, a protein involved in DNA repair and proteasomal degradation processes. This antibody, generated in rabbits, is highly specific to human RAD23A and is suitable for use in Western blot applications. By binding to RAD23A, this antibody enables the detection and analysis of RAD23A protein levels in various cell types, making it ideal for studies in molecular biology and cancer research.RAD23A is a critical player in maintaining genomic stability and protein homeostasis, making it a key target for research in diseases such as cancer and neurodegenerative disorders.
Understanding the function and regulation of RAD23A is essential for developing targeted therapies that can potentially exploit the protein's role in cellular processes. The RAD23A Polyclonal Antibody provides researchers with a reliable tool to investigate the function of RAD23A and its implications in disease pathology.
Product Name:
Rad23A Polyclonal Antibody
SKU:
CAB21585
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-363 of human Rad23A (NP_005044.1).
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
Purification Method:
Affinity purification
Gene ID:
5886
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Rad23A antibody (CAB21585) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
