Rad18 Rabbit Monoclonal Antibody (CAB4339)
- SKU:
- CAB4339
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Rad18 Rabbit Monoclonal Antibody |
SKU: | CAB4339 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rad18 (Q9NS91). |
Sequence: | MDSL AESR WPPG LAVM KTID DLLR CGIC FEYF NIAM IIPQ CSHN YCSL CIRK FLSY KTQC PTCC VTVT EPDL KNNR ILDE LVKS LNFA RNHL LQFA LESP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | RNF73; Rad18 |
Positive Sample: | HeLa,A-549,MCF7,K-562,Mouse testis,Mouse brain,Mouse spleen,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 56kDa |
Observed MW: | 70kDa/90kDa |
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Purification Method: | Affinity purification |
Gene ID: | 56852 |
Clone Number: | ARC1058 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |