The Rack1 Rabbit Monoclonal Antibody (CAB3808) is a vital tool for research involving Rack1, a multifunctional protein involved in various cellular processes such as ribosome biogenesis, cell proliferation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as immunofluorescence and flow cytometry. It specifically targets the Rack1 protein, enabling precise detection and analysis in different cell types.Rack1, also known as receptor for activated C kinase 1, plays a crucial role in signal transduction pathways and protein kinase C activation, making it a key player in cell signaling networks.
Its involvement in various cellular functions underscores its importance in physiological and pathological processes, making it a promising target for research in areas such as cancer, neurodegenerative diseases, and cardiovascular disorders. Understanding the functions and interactions of Rack1 is essential for unraveling its role in disease development and progression, and ultimately for developing targeted therapies.
Product Name:
RACK1 Rabbit Monoclonal Antibody
SKU:
CAB3808
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human RACK1 (P63244).
Enables several functions, including cyclin binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of hydrolase activity; regulation of cellular protein metabolic process; and regulation of signal transduction. Located in several cellular components, including midbody; perinuclear region of cytoplasm; and phagocytic cup. Part of IRE1-RACK1-PP2A complex.
Purification Method:
Affinity purification
Gene ID:
10399
Clone Number:
ARC0837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RACK1 Rabbit mAb (CAB3808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
