RGAP1 Rabbit Polyclonal Antibody (CAB5298)
- SKU:
- CAB5298
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | RGAP1 Rabbit Polyclonal Antibody |
SKU: | CAB5298 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 353-632 of human RGAP1 (NP_001119576.1). |
Sequence: | DFVS QTSP MIPS IVVH CVNE IEQR GLTE TGLY RISG CDRT VKEL KEKF LRVK TVPL LSKV DDIH AICS LLKD FLRN LKEP LLTF RLNR AFME AAEI TDED NSIA AMYQ AVGE LPQA NRDT LAFL MIHL QRVA QSPH TKMD VANL AKVF GPTI VAHA VPNP DPVT MLQD IKRQ PKVV ERLL SLPL EYWS QFMM VEQE NIDP LHVI ENSN AFST PQTP DIKV SLLG PVTT PEHQ LLKT PSSS SLSQ RVRS TLTK NTPR FGSK SKSA TNLG RQGN FFAS PMLK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CYK4; CDAN3B; ID-GAP; HsCYK-4; MgcRacGAP; RGAP1 |
Positive Sample: | HeLa,293T,K-562,Mouse testis,Mouse thymus,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cleavage furrow, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Midbody, Nucleus, Peripheral membrane protein, acrosome, cytoskeleton, secretory vesicle, spindle. |
Calculated MW: | 71kDa |
Observed MW: | 71kDa |
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Purification Method: | Affinity purification |
Gene ID: | 29127 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |