RGAP1 Rabbit Monoclonal Antibody (CAB19236)
- SKU:
- CAB19236
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- RACGAP1
- CYK4
- HsCYK-4
- ID-GAP
- MgcRacGAP
- rac GTPase-activating protein 1
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | RGAP1 Rabbit Monoclonal Antibody |
SKU: | CAB19236 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RGAP1 (Q9H0H5). |
Sequence: | MDTM MLNV RNLF EQLV RRVE ILSE GNEV QFIQ LAKD FEDF RKKW QRTD HELG KYKD LLMK AETE RSAL DVKL KHAR NQVD VEIK RRQR AEAD CEKL ERQI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CYK4; CDAN3B; ID-GAP; HsCYK-4; MgcRacGAP; RGAP1 |
Positive Sample: | 293T,NIH/3T3,K-562,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cleavage furrow, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Midbody, Nucleus, Peripheral membrane protein, acrosome, cytoskeleton, secretory vesicle, spindle. |
Calculated MW: | 71kDa |
Observed MW: | 70kDa |
This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.
Purification Method: | Affinity purification |
Gene ID: | 29127 |
Clone Number: | ARC2394 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |