The RAC2 Polyclonal Antibody (CAB1139) is a valuable tool for researchers studying the RAC2 protein, a key regulator of cellular signaling pathways involved in immune response and cell migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.RAC2 plays a critical role in immune cell function, particularly in processes such as phagocytosis and superoxide production. Dysregulation of RAC2 activity has been implicated in various diseases, including cancer, inflammatory disorders, and immune deficiencies.
By targeting RAC2 with this polyclonal antibody, researchers can accurately detect and analyze RAC2 expression in different cell types, providing valuable insights into its role in health and disease. With its high reactivity and specificity, the RAC2 Polyclonal Antibody (CAB1139) is a reliable tool for investigating the functions of RAC2 and its potential as a therapeutic target in immune-related conditions. Whether studying immune regulation, cancer biology, or inflammatory diseases, this antibody is a valuable asset for any laboratory conducting research in these areas.
Product Name:
RAC2 Rabbit Polyclonal Antibody
SKU:
CAB1139
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-192 of human RAC2 (NP_002863.1).
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6.
Purification Method:
Affinity purification
Gene ID:
5880
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RAC2 Rabbit pAb (CAB1139) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
