The RAC1/2/3 Polyclonal Antibody (CAB21584) is a valuable tool for researchers studying RAC1, RAC2, and RAC3 proteins, which play key roles in cellular signaling pathways involved in cell migration, proliferation, and survival. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.RAC proteins are members of the Rho family of GTPases and are essential for regulating cytoskeletal dynamics and cell motility. Dysregulation of RAC signaling has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions.
This antibody binds specifically to RAC1, RAC2, and RAC3 proteins, allowing for their detection and quantification in a wide range of cell types.By enabling detailed analysis of RAC protein expression and activity, the RAC1/2/3 Polyclonal Antibody is an invaluable tool for research in cell biology, cancer biology, and drug development. Understanding the functions of RAC proteins and their implications in disease pathogenesis is crucial for the development of targeted therapies aimed at modulating cellular signaling pathways for therapeutic benefit.
Product Name:
Rac1/2/3 Polyclonal Antibody
SKU:
CAB21584
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human Rac1/2/3 (NP_008839.2).
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5879
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of C6 cells using Rac1/2/3 Rabbit pAb (CAB21584) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
