The Rabphilin 3A Polyclonal Antibody (CAB6722) is a vital tool for researchers studying Rabphilin 3A, a key protein involved in synaptic vesicle trafficking and neurotransmitter release. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting and immunofluorescence applications.Rabphilin 3A is a crucial regulator of synaptic vesicle exocytosis, making it essential for proper neurotransmission and neuronal function. Dysregulation of Rabphilin 3A has been linked to neurological disorders such as epilepsy and neurodegenerative diseases, highlighting its importance in the brain.
By utilizing the Rabphilin 3A Polyclonal Antibody (CAB6722), researchers can effectively study the expression and localization of Rabphilin 3A in various cell types and tissues, providing valuable insights into its function and potential therapeutic targets for neurological conditions. This antibody is a valuable tool for those working in neuroscience, neurology, and molecular biology research.
Product Name:
RPH3A Rabbit Polyclonal Antibody
SKU:
CAB6722
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human RPH3A (NP_055769.2).
The protein encoded by this gene is thought to be an effector for RAB3A, which is a small G protein that acts in the late stages of neurotransmitter exocytosis. The encoded protein may be involved in neurotransmitter release and synaptic vesicle traffic.
Purification Method:
Affinity purification
Gene ID:
22895
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RPH3A antibody (CAB6722) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
