The RABL3 Polyclonal Antibody (CAB14327) is a valuable tool for research involving RABL3, a member of the RAS oncogene family involved in cell signaling and intracellular transport processes. This antibody, produced in rabbits, is highly specific for detecting RABL3 in human samples and is validated for use in Western blot applications. By targeting the RABL3 protein, this antibody allows for the precise detection and analysis of RABL3 expression in various cell types, making it an excellent choice for studies in cell biology and cancer research.RABL3 plays a crucial role in regulating intracellular vesicle trafficking and membrane dynamics, making it a key player in cellular processes such as endocytosis and membrane recycling.
Dysregulation of RABL3 has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target. By using the RABL3 Polyclonal Antibody, researchers can gain valuable insights into the function of RABL3 and its role in disease pathology, ultimately paving the way for the development of targeted therapies aimed at correcting RABL3-related dysfunctions.
Product Name:
RABL3 Rabbit Polyclonal Antibody
SKU:
CAB14327
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human RABL3 (NP_776186.2).
Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in regulation of Ras protein signal transduction and regulation of protein lipidation. Predicted to be active in endomembrane system. Implicated in pancreatic cancer.
Purification Method:
Affinity purification
Gene ID:
285282
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RABL3 Rabbit pAb (CAB14327) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
