The RabGap1L Polyclonal Antibody (PAC046622) is a valuable tool for researchers studying RabGap1L, a protein involved in regulating intracellular transport and vesicle trafficking. This antibody is produced in rabbits and has been validated for use in Western blot applications, demonstrating high reactivity with human samples.RabGap1L is a key player in the dynamic process of vesicle trafficking within cells, influencing important cellular functions such as protein sorting and membrane fusion. Dysregulation of RabGap1L has been associated with various diseases, including cancer and neurological disorders, making it an attractive target for further research.
By utilizing the RabGap1L Polyclonal Antibody, researchers can effectively detect and analyze RabGap1L protein levels in a variety of cell types, providing insights into its role in cellular processes and disease pathogenesis. This antibody is instrumental in advancing our understanding of RabGap1L function and its potential implications for therapeutic development in related fields.
Immunohistochemistry of paraffin-embedded human liver cancer using PACO46622 at dilution of 1:100.
Western Blot. Positive WB detected in: MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, Mouse stomach tissue, Mouse heart tissue, Mouse brain tissue, Mouse liver tissue. All lanes: RABGAP1L antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 30, 93, 69, 95, 91, 44, 42, 43, 9 kDa. Observed band size: 30 kDa.
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO46622 at dilution of 1:100.
Synonyms:
Rab GTPase-activating protein 1-like, isoform 10, RABGAP1L, HHL KIAA0471
UniProt Protein Function:
Induction: Up-regulated in esophageal squamous cell carcinomas. Expression is strongly inhibited in the medial septum and hippocampus brain regions of some Alzheimer disease patients. Ref.10 Ref.11
