The RABEP2 Polyclonal Antibody (PAC041634) is a valuable tool for researchers studying the RABEP2 protein, which plays a key role in regulating vesicle trafficking and membrane fusion within cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications.RABEP2 is essential for the proper functioning of intracellular transport pathways, making it a pivotal player in various cellular processes such as protein sorting, recycling, and secretion.
By targeting the RABEP2 protein, researchers can gain insights into the mechanisms underlying these important cellular functions.With its reactivity to RABEP2 and ability to facilitate detection and analysis in diverse cell types, this antibody is an invaluable tool for studies in cell biology, molecular biology, and neurology. By understanding the role of RABEP2 in cellular processes, researchers can potentially uncover new pathways for therapeutic intervention in conditions related to vesicle trafficking dysfunction.
Antibody Name:
RABEP2 Antibody (PACO41634)
Antibody SKU:
PACO41634
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Rab GTPase-binding effector protein 2 protein (301-533AA)
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO41634 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO41634 at dilution of 1:100.
Background:
Plays a role in membrane trafficking and in homotypic early endosome fusion.
Synonyms:
Rab GTPase-binding effector protein 2 (Rabaptin-5beta), RABEP2, RABPT5B
UniProt Protein Function:
RABEP2: Plays a role in membrane trafficking and in homotypic early endosome fusion. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rab; GAPsChromosomal Location of Human Ortholog: 16p11.2Cellular Component: intracellular membrane-bound organelle; early endosome; cytoplasmMolecular Function: growth factor activity; GTPase activator activityBiological Process: protein transport; endocytosis; positive regulation of GTPase activity
