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RABEP1 Antibody (PACO11676)

SKU:
PACO11676
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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RABEP1 Antibody (PACO11676)

The RABEP1 Polyclonal Antibody (PACO11676) is a valuable tool for researchers studying the RABEP1 protein, which plays a key role in regulating membrane traffic and endocytosis. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the RABEP1 protein, this antibody allows for the detection and analysis of RABEP1 in various cell types, making it ideal for studies in cell biology and molecular biology.

RABEP1 is a crucial component involved in the intracellular trafficking of vesicles, particularly in the endocytic pathway. Its role in regulating membrane dynamics and protein sorting makes it a target of interest in research related to cell trafficking, signaling, and disease mechanisms. By studying RABEP1, researchers can gain insights into cellular processes and potentially identify new therapeutic targets for diseases related to membrane trafficking dysfunction.

Antibody Name:RABEP1 Antibody (PACO11676)
Antibody SKU:PACO11676
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human RABEP1
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:rabaptin, RAB GTPase binding effector protein 1;RABEP1;RAB5EP;RABPT5 ;
UniProt Protein Function:RABEP1: Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: recycling endosome; intracellular membrane-bound organelle; endocytic vesicle; early endosome; endosome

Molecular Function:protein binding; protein homodimerization activity; growth factor activity; GTPase activator activity

Biological Process: vesicle-mediated transport; protein transport; apoptosis; endocytosis; positive regulation of GTPase activity

UniProt Code:Q15276
NCBI GenInfo Identifier:116242743
NCBI Gene ID:9135
NCBI Accession:Q15276.2
UniProt Secondary Accession:Q15276,O95369, Q8IVX3, B2RAG7,
UniProt Related Accession:Q15276
Molecular Weight:862
NCBI Full Name:Rab GTPase-binding effector protein 1
NCBI Synonym Full Names:rabaptin, RAB GTPase binding effector protein 1
NCBI Official Symbol:RABEP1  
NCBI Official Synonym Symbols:RAB5EP; RABPT5  
NCBI Protein Information:rab GTPase-binding effector protein 1; rabaptin-4; rabaptin-5; neurocrescin; rabaptin-5alpha; renal carcinoma antigen NY-REN-17
UniProt Protein Name:Rab GTPase-binding effector protein 1
UniProt Synonym Protein Names:Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17
Protein Family:Rab GTPase-binding effector protein
UniProt Gene Name:RABEP1  
UniProt Entry Name:RABE1_HUMAN

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