null

RABEP1 Antibody (PACO05696)

SKU:
PACO05696
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

RABEP1 Antibody (PACO05696)

The RABEP1 Polyclonal Antibody (PACO05696) is a powerful tool for research into RABEP1, a protein involved in regulating membrane trafficking and vesicle fusion processes within cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it a reliable choice for immunological studies and cancer research.RABEP1 is essential for maintaining cellular homeostasis by mediating the transport of molecules between various cellular compartments. Dysregulation of RABEP1 has been implicated in diseases such as cancer, neurodegenerative disorders, and infectious diseases.

By targeting RABEP1 with this antibody, researchers can gain insight into its function and potential therapeutic applications in these disease contexts.With its ability to detect and analyze RABEP1 in a variety of cell types, the RABEP1 Polyclonal Antibody is a valuable tool for investigating the role of this protein in cellular processes and disease pathogenesis. Researchers can utilize this antibody in Western blot assays to elucidate the molecular mechanisms underlying RABEP1 function, paving the way for novel therapeutic strategies targeting RABEP1 in the future.

Antibody Name:RABEP1 Antibody (PACO05696)
Antibody SKU:PACO05696
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:40000, IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:Synthesized peptide derived from the Internal region of human Rabaptin-5 α .
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:RABEP1; RAB5EP; RABPT5; RABPT5A; Rab GTPase-binding effector protein 1; Rabaptin-4; Rabaptin-5; Rabaptin-5α; Renal carcinoma antigen NY-REN-17
UniProt Protein Function:RABEP1: Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle

Chromosomal Location of Human Ortholog: 17p13.2

Cellular Component: recycling endosome; intracellular membrane-bound organelle; endocytic vesicle; early endosome; endosome

Molecular Function:protein binding; protein homodimerization activity; growth factor activity; GTPase activator activity

Biological Process: vesicle-mediated transport; protein transport; apoptosis; endocytosis; positive regulation of GTPase activity

UniProt Code:Q15276
NCBI GenInfo Identifier:116242743
NCBI Gene ID:9135
NCBI Accession:Q15276.2
UniProt Secondary Accession:Q15276,O95369, Q8IVX3, B2RAG7,
UniProt Related Accession:Q15276
Molecular Weight:862
NCBI Full Name:Rab GTPase-binding effector protein 1
NCBI Synonym Full Names:rabaptin, RAB GTPase binding effector protein 1
NCBI Official Symbol:RABEP1  
NCBI Official Synonym Symbols:RAB5EP; RABPT5  
NCBI Protein Information:rab GTPase-binding effector protein 1; rabaptin-4; rabaptin-5; neurocrescin; rabaptin-5alpha; renal carcinoma antigen NY-REN-17
UniProt Protein Name:Rab GTPase-binding effector protein 1
UniProt Synonym Protein Names:Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17
Protein Family:Rab GTPase-binding effector protein
UniProt Gene Name:RABEP1  
UniProt Entry Name:RABE1_HUMAN

Related Products