Rabbit IL1B Recombinant Protein (His tag) (RPES6805)
- SKU:
- RPES6805
- Product Type:
- Recombinant Protein
- Species:
- Rabbit
Frequently bought together:
Description
| Product Name: | Rabbit IL1B Recombinant Protein (His tag) |
| Product Code: | RPES6805 |
| Size: | 20µg |
| Species: | Rabbit |
| Expression Host: | E.coli |
| Synonyms: | IL-1 beta, Lymphocyte proliferation-potentiating factor, IL-1B |
| Mol Mass: | 17 kDa |
| AP Mol Mass: | 17 kDa |
| Tag: | N-His |
| Purity: | > 80 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Bio Activity: | Testing in progress |
| Sequence: | Ala117-Ser268 |
| Accession: | P14628 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. |
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