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Rabbit IL1B Recombinant Protein (His tag) (RPES6805)

SKU:
RPES6805
Product Type:
Recombinant Protein
Species:
Rabbit
$155
Frequently bought together:

Description

Product Name:Rabbit IL1B Recombinant Protein (His tag)
Product Code:RPES6805
Size:20µg
Species:Rabbit
Expression Host:E.coli
Synonyms:IL-1 beta, Lymphocyte proliferation-potentiating factor, IL-1B
Mol Mass:17 kDa
AP Mol Mass:17 kDa
Tag:N-His
Purity:> 80 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Ala117-Ser268
Accession:P14628
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

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