RAB7 Rabbit Polyclonal Antibody (CAB12784)
- SKU:
- CAB12784
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | RAB7 Rabbit Polyclonal Antibody |
SKU: | CAB12784 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-207 of human RAB7 (NP_004628.4). |
Sequence: | DSWR DEFL IQAS PRDP ENFP FVVL GNKI DLEN RQVA TKRA QAWC YSKN NIPY FETS AKEA INVE QAFQ TIAR NALK QETE VELY NEFP EPIK LDKN DRAK ASAE SCSC |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | RAB7; CMT2B; PRO2706 |
Positive Sample: | HeLa,Neuro-2a,C2C12,Mouse brain,PC-12,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic side, Cytoplasmic vesicle, Late endosome membrane, Lipid droplet, Lysosome membrane, Melanosome membrane, Peripheral membrane protein, autophagosome membrane, phagosome membrane. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Purification Method: | Affinity purification |
Gene ID: | 7879 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |