RAB7A Monoclonal Antibody [PAT10E4AT] (CPAB0676)
- SKU:
- CPAB0676
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT10E4AT
- Applications:
- WB
- ELISA
Description
RAB7A Monoclonal Antibody [PAT10E4AT] (CPAB0676)
The Rab7A Polyclonal Antibody (CPAB0676) is a valuable tool for researchers studying Rab7A, a small GTPase known for its role in endosome-lysosome fusion and intracellular trafficking. This antibody, produced in rabbits, demonstrates high specificity and sensitivity when detecting Rab7A in human samples, making it ideal for use in Western blotting experiments.Rab7A plays a crucial role in the regulation of vesicular trafficking and lysosomal degradation pathways, making it essential for cellular processes such as autophagy and endocytosis. Dysregulation of Rab7A has been implicated in various diseases, including neurodegenerative disorders and cancer, highlighting the importance of studying its function.
By using the Rab7A Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying Rab7A-mediated processes and explore its potential as a therapeutic target for diseases characterized by impaired vesicular trafficking. This antibody is a valuable tool for studies in cell biology, neuroscience, and oncology, providing researchers with the means to further elucidate the role of Rab7A in health and disease.
Product Name: | RAB7A Antibody |
Product Sku: | CPAB0676 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human RAB7A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human RAB7A protein 1-27 amino acids purified from Ecoli. |
Clone: | PAT10E4AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | RAB7A antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | RAB7A belongs to the Ras superfamily of small Rab GTPases. RAB7A connects with the RIPL effector protein to regulator membrane trafficking from early to late endosome and to lysosomes. RAB7A can also regulate growth receptor endocytic trafficking, degradation, maturation of phagosome and autophagic vacuoles. |
Synonyms: | RAB7A member RAS oncogene family, RAB7, ras-related protein Rab-7a, FLJ20819, PSN, CMT2B, PRO2706. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |