The Rab6C Polyclonal Antibody (PAC020303) is a high-quality research tool specifically designed for investigating Rab6C, a member of the Rab family of small GTPases involved in intracellular vesicle trafficking. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blotting, immunofluorescence, and immunoprecipitation applications.Rab6C plays a crucial role in the regulation of vesicle transport between the Golgi apparatus and the endoplasmic reticulum, as well as in protein sorting and membrane trafficking. Its dysregulation has been implicated in various diseases, including neurodegenerative disorders and cancer.
The Rab6C Polyclonal Antibody enables the detection and analysis of Rab6C expression in different cell types and tissues, making it an invaluable tool for studies in cell biology, molecular biology, and disease research.By providing researchers with a reliable and specific tool for studying Rab6C, this antibody facilitates a better understanding of the cellular mechanisms involving Rab6C and its potential implications in disease pathogenesis. Its versatility in various experimental techniques makes it an essential reagent for investigating the roles of Rab6C in intracellular trafficking and signaling pathways.
Antibody Name:
RAB6C Antibody (PACO20303)
Antibody SKU:
PACO20303
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human RAB6C
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20303(RAB6C Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20303(RAB6C Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Ras-related protein Rab-6C is a protein that in humans is encoded by the RAB6C gene. May be involved in the regulation of centrosome duplication and cell cycle progression. Highest levels are found in fetal and adult brain, prostate, testis and spinal cord.