The Rab6B Polyclonal Antibody (PACO11669) is a valuable tool for researchers studying Rab6B, a member of the Rab family of small GTPases involved in intracellular trafficking processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to Rab6B protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in cell biology and molecular biology fields.Rab6B plays a crucial role in regulating vesicular transport and membrane trafficking pathways within the cell, making it a key player in processes such as protein sorting, secretion, and signal transduction.
Dysregulation of Rab6B has been associated with various diseases, including neurological disorders and cancer, highlighting its importance in cellular homeostasis and disease pathogenesis. By studying Rab6B activity, researchers can gain insights into intracellular trafficking mechanisms and potentially discover new therapeutic targets for related diseases.
RAB6B: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric, Rab; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: 3q22.1Cellular Component: Golgi apparatusMolecular Function: myosin V binding; protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
