RAB6A Rabbit Polyclonal Antibody (CAB5613)
- SKU:
- CAB5613
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | RAB6A Rabbit Polyclonal Antibody |
SKU: | CAB5613 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB6A (NP_002860.2). |
Sequence: | MSTG GDFG NPLR KFKL VFLG EQSV GKTS LITR FMYD SFDN TYQA TIGI DFLS KTMY LEDR TIRL QLWD TAGQ ERFR SLIP SYIR DSAA AVVV YDIT NVNS FQQT TKWI DDVR TERG SDVI IMLV GNKT DLAD KRQV SIEE GERK AKEL NVMF IETS AKAG YNVK QLFR RVAA ALPG MEST QDRS REDM IDIK LEKP QEQP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RAB6; RAB6A |
Positive Sample: | BT-474,OVCAR3,SW480,HT-29,293T,SH-SY5Y,Mouse brain,Mouse lung,Mouse intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, Golgi apparatus membrane, Lipid-anchor. |
Calculated MW: | 24kDa |
Observed MW: | 33kDa |
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 5870 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |