The Rab5C Polyclonal Antibody (CAB7342) is a valuable tool for researchers studying Rab5C, a small GTPase involved in regulating endocytic trafficking and membrane fusion processes within cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting Rab5C in human samples, making it ideal for use in Western blot applications.Rab5C is a key player in the endocytic pathway, controlling the trafficking of vesicles and cargo molecules to various cellular compartments.
Dysregulation of Rab5C has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its importance as a potential therapeutic target. By utilizing the Rab5C Polyclonal Antibody, researchers can investigate the role of Rab5C in cellular processes and disease pathogenesis, ultimately leading to a better understanding of its functions and potential clinical applications.
Product Name:
RAB5C Rabbit Polyclonal Antibody
SKU:
CAB7342
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-216 of human RAB5C (NP_958842.1).
Cell membrane, Cytoplasmic side, Early endosome membrane, Lipid-anchor, Melanosome.
Calculated MW:
23kDa
Observed MW:
23kDa
Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).
Purification Method:
Affinity purification
Gene ID:
5878
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB5C antibody (CAB7342) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
