RAB5A Monoclonal Antibody [P3A4AT] (CPAB0522)
- SKU:
- CPAB0522
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- P3A4AT
- Applications:
- WB
- ELISA
Description
RAB5A Monoclonal Antibody [P3A4AT] (CPAB0522)
The Rab5A Polyclonal Antibody (CPAB0522) is a valuable tool for researchers studying Rab5A, a small GTPase protein involved in regulating endocytic trafficking and membrane fusion processes within cells. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.Rab5A is a key player in the endocytic pathway, controlling the formation of early endosomes and facilitating the sorting of cargo molecules. Dysregulation of Rab5A has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting Rab5A with this antibody, researchers can better understand its role in these conditions and potentially identify new therapeutic targets.The Rab5A Polyclonal Antibody allows for the detection and analysis of Rab5A protein expression in different cell types, providing valuable insights into its function and localization within the cell. Its high reactivity and specificity make it a reliable reagent for studies in cell biology, cancer research, and other fields where Rab5A is of interest. Unlock the potential of Rab5A research with this versatile antibody.
Product Name: | RAB5A Antibody |
Product Sku: | CPAB0522 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human RAB5A mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human RAB5A amino acids 1-215 purified from Ecoli. |
Clone: | P3A4AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | RAB5A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | RAB5A is a member of RAS oncogene family. The small GTPase, RAB5A is a crucial regulatory component of the endocytic pathway. Activation of RAB5A is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex). RAB5A is required for the fusion of plasma membranes and early endosomes. |
Synonyms: | Ras-related protein Rab-5A, RAB5A, RAB5. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |