The Rab4A Polyclonal Antibody (CAB6712) is a vital tool for researchers studying Rab4A, a small GTPase involved in regulating endocytic trafficking. This antibody, generated in rabbits, has high specificity and sensitivity for detecting Rab4A in human samples, making it an ideal choice for Western blot experiments.Rab4A is crucial for controlling the recycling of proteins from endosomes back to the cell surface, a process that is essential for maintaining cell function and homeostasis. Dysregulation of Rab4A has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic intervention.
By using the Rab4A Polyclonal Antibody, researchers can gain valuable insights into the role of Rab4A in intracellular trafficking pathways and its potential implications in disease pathology. This antibody is a valuable tool for studies in cell biology, cancer research, and neurobiology, providing a deeper understanding of Rab4A function and its therapeutic potential.
Product Name:
RAB4A Rabbit Polyclonal Antibody
SKU:
CAB6712
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RAB4A (NP_004569.2).
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5867
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB4A antibody (CAB6712) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
