The Rab41 Polyclonal Antibody (PACO17518) is a crucial tool for researchers studying Rab41, a small GTPase involved in intracellular vesicle trafficking. This antibody, raised in rabbits, is highly specific for detecting Rab41 in human samples and is validated for use in various applications, including Western blot and immunofluorescence.Rab41 is known to play a key role in controlling vesicular transport processes within cells, making it essential for proper cellular function. Studies have shown that dysregulation of Rab41 can lead to disruption of intracellular trafficking pathways, resulting in various cellular and physiological defects. As such, understanding the function and regulation of Rab41 is critical for unraveling its involvement in diseases such as neurodegenerative disorders, cancer, and infectious diseases.
With its high specificity and sensitivity, the Rab41 Polyclonal Antibody (PACO17518) is an invaluable tool for researchers investigating the role of Rab41 in health and disease. Its ability to detect Rab41 in different cell types and tissues makes it a versatile option for studies in cell biology, molecular biology, and pharmacology. Unlock the mysteries of Rab41 with this reliable antibody and advance your research in the field of intracellular vesicle trafficking.
Antibody Name:
RAB41 Antibody (PACO17518)
Antibody SKU:
PACO17518
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human RAB41
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17518(RAB41 Antibody) at dilution 1/60. (Original magnification: x200).
The image is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO17518(RAB41 Antibody) at dilution 1/60. (Original magnification: x200).
Background:
This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex.
Synonyms:
Ras-related protein Rab-41
UniProt Protein Function:
RAB41: a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]Protein type: G protein, monomeric, Rab; G protein; G protein, monomericChromosomal Location of Human Ortholog: Xq13.1Cellular Component: Golgi apparatus; Golgi membraneMolecular Function: protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
UniProt Protein Details:
NCBI Summary:
This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]
