The RAB41 Polyclonal Antibody (PACO04123) is a valuable tool for researchers studying RAB41, a member of the RAB family of small GTPases involved in intracellular membrane trafficking. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the RAB41 protein, this antibody allows for the detection and analysis of RAB41 expression in various cell types, making it an essential component of studies in cell biology and molecular biology.RAB41 is known to play a crucial role in regulating vesicular transport and membrane dynamics within cells, making it a key player in processes such as endocytosis, exocytosis, and organelle trafficking.
Dysregulation of RAB41 has been implicated in various diseases, including neurodegenerative disorders and cancer. By studying the function and expression of RAB41, researchers can gain important insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.The RAB41 Polyclonal Antibody (PACO04123) offers high sensitivity and specificity, making it an invaluable tool for researchers looking to unravel the complex roles of RAB41 in cellular processes and disease pathogenesis. Its versatility and reliability make it a must-have reagent for studies in cell biology, molecular biology, and disease research.
Antibody Name:
RAB41 Antibody
Antibody SKU:
PACO04123
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Rab 41.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RAB41; Ras-related protein Rab-41
UniProt Protein Function:
RAB41: a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]Protein type: G protein, monomeric, Rab; G protein; G protein, monomericChromosomal Location of Human Ortholog: Xq13.1Cellular Component: Golgi apparatus; Golgi membraneMolecular Function: protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
UniProt Protein Details:
NCBI Summary:
This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex. [provided by RefSeq, May 2010]
