Based on the information in the provided URL, the Rab40B Antibody (PAC002383) is a valuable tool for researchers studying the Rab40B protein, an important member of the Rab GTPase family involved in intracellular membrane trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples, making it an ideal choice for experiments investigating the function and localization of Rab40B in various cellular processes.With its validated use in Western blot applications, this antibody specifically targets the Rab40B protein, allowing for accurate detection and analysis in different cell types. By utilizing this antibody, researchers can gain insights into the role of Rab40B in cellular trafficking pathways, which is essential for understanding its implications in various diseases and biological processes.
The Rab40B Antibody (PAC002383) is a valuable asset for scientists interested in molecular biology, cell biology, and cancer research, as it provides a reliable tool for investigating the intricate mechanisms underlying Rab40B function. Through further exploration of Rab40B's involvement in cellular processes, researchers can potentially uncover new therapeutic targets and strategies for treating diseases associated with dysregulated membrane trafficking.
Antibody Name:
RAB40B Antibody
Antibody SKU:
PACO02383
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Rab 40B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RAB40B; SEC4L; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Protein Rar
UniProt Protein Function:
RAB40B: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein; G protein, monomeric; G protein, monomeric, RabChromosomal Location of Human Ortholog: 17q25.3Cellular Component: plasma membrane; endosome membraneMolecular Function: GTPase activity; GDP binding; GTP bindingBiological Process: regulation of exocytosis; intracellular protein transport; protein secretion; protein ubiquitination; Rab protein signal transduction; vesicle docking during exocytosis
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008]
