The Rab3IL1 Polyclonal Antibody (PAC038598) is a valuable tool for researchers studying Rab3IL1, a protein involved in intracellular membrane trafficking and vesicle transport. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting Rab3IL1, researchers can analyze its expression and function in different cell types, offering insight into its role in cellular processes.Rab3IL1 is a key player in regulating vesicle transport within cells, making it essential for processes such as neurotransmitter release and hormone secretion. Its involvement in membrane trafficking pathways highlights its importance in various physiological functions, including synaptic transmission and signal transduction.
Research on Rab3IL1 can provide valuable information on cell communication and coordination, making it a promising target for studies in cell biology and neurobiology.By utilizing the Rab3IL1 Polyclonal Antibody, researchers can gain a better understanding of the molecular mechanisms involving Rab3IL1, paving the way for new insights into cellular processes and potential therapeutic targets. Its specificity and reliability make it a valuable asset for investigations into intracellular trafficking and vesicle transport pathways.
Antibody Name:
RAB3IL1 Antibody (PACO38598)
Antibody SKU:
PACO38598
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Guanine nucleotide exchange factor for Rab-3A protein (1-200AA)
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B.
Synonyms:
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1), RAB3IL1
UniProt Protein Function:
RAB3IL1: Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis. Belongs to the SEC2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rab; GEFsChromosomal Location of Human Ortholog: 11q12.2Molecular Function: protein binding; Rab guanyl-nucleotide exchange factor activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012]
