The RAB3IL1 Polyclonal Antibody (PACO11660) is a crucial tool for researchers studying the RAB3IL1 protein, involved in intracellular membrane trafficking and vesicle transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to RAB3IL1, this antibody enables precise detection and analysis of the protein in various cell types, making it a valuable asset for studies in cell biology and neurobiology research.RAB3IL1 plays a key role in regulating vesicle fusion and neurotransmitter release, making it essential for processes like synaptic transmission and neuronal communication.
Understanding the function and regulation of RAB3IL1 is critical for unraveling the mechanisms underlying neurological disorders and synaptic dysfunction. By targeting RAB3IL1, researchers can gain insights into the molecular pathways involved in synaptic vesicle trafficking and potentially identify new therapeutic strategies for neurological conditions.
RAB3A interacting protein (rabin3)-like 1;RAB3IL1;GRAB ;
UniProt Protein Function:
RAB3IL1: Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis. Belongs to the SEC2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rab; GEFsChromosomal Location of Human Ortholog: 11q12.2Molecular Function: protein binding; Rab guanyl-nucleotide exchange factor activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012]
