The Rab3GAP2 Polyclonal Antibody (CAB17669) is a valuable tool for researchers studying Rab3GAP2, a protein involved in regulating membrane trafficking and vesicle fusion. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding to Rab3GAP2, it allows for the detection and analysis of this protein in various cell types, making it ideal for studies in cell biology and neuroscience.Rab3GAP2 is a key player in the process of vesicle trafficking and neurotransmitter release, making it essential for proper neuronal function.
Dysregulation of Rab3GAP2 has been implicated in neurodevelopmental disorders and neurodegenerative diseases, highlighting its importance in cellular processes. Research on Rab3GAP2 using this antibody can provide valuable insights into synaptic transmission and neurological disorders, paving the way for potential therapeutic interventions targeting these pathways.
Product Name:
RAB3GAP2 Rabbit Polyclonal Antibody
SKU:
CAB17669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB3GAP2 (NP_036546.2).
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
Purification Method:
Affinity purification
Gene ID:
25782
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB3GAP2 Rabbit pAb (CAB17669) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
