The Rab3GAP1 Polyclonal Antibody (CAB18587) is a valuable tool for researchers studying Rab3GAP1, a key protein involved in membrane trafficking and vesicle fusion processes. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to Rab3GAP1, this antibody enables precise detection and analysis of the protein in a variety of cell types, making it ideal for investigations in cell biology and neuroscience research.Rab3GAP1 is known for its role in regulating vesicle trafficking and neurotransmitter release, making it essential for proper neuronal function.
Dysregulation of Rab3GAP1 has been implicated in neurodegenerative diseases such as Parkinson's and Alzheimer's, highlighting the importance of studying this protein in neurobiology research. The Rab3GAP1 Polyclonal Antibody provides researchers with a reliable tool to explore the function and expression of Rab3GAP1 in health and disease, paving the way for potential therapeutic interventions targeting this essential protein.
Product Name:
RAB3GAP1 Rabbit Polyclonal Antibody
SKU:
CAB18587
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-780 of human RAB3GAP1 (NP_001165906.1).
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
22930
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB3GAP1 Rabbit pAb (CAB18587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
