The Rab3D Polyclonal Antibody (CAB10390) is a valuable tool for researchers studying Rab3D, a member of the Rab GTPase family known to regulate vesicle trafficking and exocytosis. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By targeting the Rab3D protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and neurobiology.
Rab3D plays a crucial role in controlling vesicle transport and secretion in cells, particularly in neuronal and exocrine systems. Dysregulation of Rab3D has been linked to various diseases, making it a potential therapeutic target for conditions such as neurological disorders and endocrine-related diseases. Understanding the function and regulation of Rab3D is essential for unraveling its role in cellular processes and identifying potential interventions for associated pathologies.
Product Name:
RAB3D Rabbit Polyclonal Antibody
SKU:
CAB10390
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human RAB3D (NP_004274.1).
Enables myosin V binding activity. Involved in bone resorption and positive regulation of regulated secretory pathway. Located in cytoplasmic microtubule and secretory vesicle.
Purification Method:
Affinity purification
Gene ID:
9545
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB3D antibody (CAB10390) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
