RAB3C Antibody (PACO39294)
- SKU:
- PACO39294
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RAB3C Antibody (PACO39294)
The Rab3C Polyclonal Antibody (PACO39294) is a vital tool for researchers studying Rab3C, a protein involved in intracellular vesicle trafficking and neurotransmitter release. This antibody, produced in rabbits, has been validated for use in various research applications, particularly in Western blotting and immunofluorescence.Rab3C is a member of the Rab GTPase family that plays a key role in regulating the exocytosis of synaptic vesicles in neurons. It is essential for the precise control of neurotransmitter release, which is crucial for proper neuronal communication and synaptic plasticity. Dysregulation of Rab3C has been implicated in neurological disorders such as epilepsy and Alzheimer's disease, making it a target of interest for researchers in the field.
By using the Rab3C Polyclonal Antibody, researchers can effectively study the expression and localization of Rab3C in various cell types and tissues. This antibody enables the detection and analysis of Rab3C protein levels, allowing for deeper insights into its function in neuronal physiology and pathology. Ultimately, understanding the role of Rab3C may lead to the development of novel therapeutic strategies for neurodegenerative diseases and other neurological conditions.
| Antibody Name: | RAB3C Antibody (PACO39294) |
| Antibody SKU: | PACO39294 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Ras-related protein Rab-3C protein (1-227AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: RAB3C antibody at 2µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 26 kDa. Observed band size: 26 kDa. |
| Background: | Protein transport. Probably involved in vesicular traffic. |
| Synonyms: | Ras-related protein Rab-3C, RAB3C |
| UniProt Protein Function: | RAB3C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 5q13 Cellular Component: synaptic vesicle; secretory granule membrane; perinuclear region of cytoplasm; plasma membrane; cytosol; vesicle; endosome Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding Biological Process: regulation of exocytosis; intracellular protein transport; antigen processing and presentation; synaptic vesicle exocytosis; metabolic process; protein secretion; Rab protein signal transduction; vesicle docking during exocytosis |
| NCBI Summary: | This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q96E17 |
| NCBI GenInfo Identifier: | 23396832 |
| NCBI Gene ID: | 115827 |
| NCBI Accession: | Q96E17.1 |
| UniProt Related Accession: | Q96E17 |
| Molecular Weight: | |
| NCBI Full Name: | Ras-related protein Rab-3C |
| NCBI Synonym Full Names: | RAB3C, member RAS oncogene family |
| NCBI Official Symbol: | RAB3CÂ Â |
| NCBI Protein Information: | ras-related protein Rab-3C |
| UniProt Protein Name: | Ras-related protein Rab-3C |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB3CÂ Â |
| UniProt Entry Name: | RAB3C_HUMAN |
| Antibodies |
| RAB3C Antibody (PACO11657) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
RAB3C Antibody (PACO11657)
RAB3C Antibody (PACO17551)
