The Rab3A Polyclonal Antibody (CAB5379) is a high-quality research tool designed for studies involving Rab3A, a small GTPase protein involved in regulated exocytosis and neurotransmitter release. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to Rab3A, the antibody allows for the detection and analysis of this important protein in various cell types, making it ideal for research in neuroscience, endocrinology, and cell biology.Rab3A is a key regulator of synaptic vesicle exocytosis and neurotransmitter release, playing a crucial role in synaptic transmission and neuronal communication. Dysregulation of Rab3A has been linked to neurological disorders such as Parkinson's disease and epilepsy, highlighting its significance in the nervous system.
By studying the function and expression of Rab3A, researchers can gain valuable insights into the mechanisms underlying synaptic transmission and potentially identify novel therapeutic targets for neurological disorders.Overall, the Rab3A Polyclonal Antibody (CAB5379) offers researchers a reliable tool for investigating the role of Rab3A in cellular processes and neurological function. Its specificity and sensitivity make it a valuable asset for studies aiming to elucidate the intricate molecular mechanisms underlying synaptic communication and neurotransmitter release.
Product Name:
RAB3A Rabbit Polyclonal Antibody
SKU:
CAB5379
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB3A (NP_002857.1).
Enables GTPase activity and myosin V binding activity. Involved in several processes, including acrosomal vesicle exocytosis; lysosome localization; and plasma membrane repair. Located in perinuclear region of cytoplasm.
Purification Method:
Affinity purification
Gene ID:
5864
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB3A Rabbit pAb (CAB5379) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
