The Rab34 Polyclonal Antibody (CAB10332) is a powerful tool for researchers studying Rab34, a small GTPase protein involved in intracellular membrane trafficking and vesicle formation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blotting and immunofluorescence applications.Rab34 is known to play a key role in maintaining cellular homeostasis by regulating processes such as endocytosis, autophagy, and organelle biogenesis. Dysregulation of Rab34 has been implicated in various diseases, including neurological disorders, cancer, and infectious diseases.
By targeting Rab34 with this polyclonal antibody, researchers can gain valuable insights into its function and potential therapeutic implications in these pathological conditions.This antibody is an essential tool for investigators seeking to elucidate the molecular mechanisms underlying Rab34-mediated cellular processes. Its specificity and sensitivity make it an ideal choice for studies in cell biology, molecular biology, and drug discovery, ultimately contributing to advancements in our understanding of disease pathogenesis and potential therapeutic targets.
Product Name:
RAB34 Rabbit Polyclonal Antibody
SKU:
CAB10332
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-259 of human RAB34 (NP_114140.4).
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame.
Purification Method:
Affinity purification
Gene ID:
83871
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB34 antibody (CAB10332) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
