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RAB34 Antibody (PACO11650)

SKU:
PACO11650
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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RAB34 Antibody (PACO11650)

The Rab34 Polyclonal Antibody (PAC011650) is a valuable tool for research involving Rab34, a small GTPase protein that plays a key role in intracellular trafficking and vesicular transport processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to Rab34 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in cell biology, molecular biology, and vesicular transport mechanisms.Rab34 is known to be involved in the regulation of vesicle trafficking between the Golgi apparatus and endosomes, as well as in the maturation of autophagosomes.

Dysfunction of Rab34 has been linked to various diseases, including neurological disorders and cancer. Research into the functions and regulation of Rab34 is essential for understanding its role in cellular processes and for developing potential therapeutic strategies targeting Rab34-related pathways.With its high specificity and reliability, the Rab34 Polyclonal Antibody (PAC011650) is an indispensable resource for researchers investigating the intricate mechanisms of intracellular vesicle trafficking and the physiological functions of Rab34 in health and disease.

Antibody Name:RAB34 Antibody (PACO11650)
Antibody SKU:PACO11650
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human RAB34
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:RAB34, member RAS oncogene family;RAB34;RAB39;RAH ;
UniProt Protein Function:NARR: May interact with EIF5A and ERF1. 3 isoforms of the human protein are produced by alternative splicing
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: Golgi apparatus; Golgi cisterna; Golgi stack; perinuclear region of cytoplasm; phagocytic vesicle; vesicle

Molecular Function:GTP-dependent protein binding; protein binding; Ral GTPase binding

Biological Process: antigen processing and presentation; Golgi to plasma membrane protein transport; lysosome localization

NCBI Summary:This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016]
UniProt Code:P0DI83
NCBI GenInfo Identifier:347602360
NCBI Gene ID:83871
NCBI Accession:P0DI83.1
UniProt Secondary Accession:P0DI83,Q9BZG1,
UniProt Related Accession:Q9BZG1
Molecular Weight:21kDa
NCBI Full Name:Ras-related protein Rab-34, isoform NARR
NCBI Synonym Full Names:RAB34, member RAS oncogene family
NCBI Official Symbol:RAB34  
NCBI Official Synonym Symbols:RAH; NARR; RAB39  
NCBI Protein Information:ras-related protein Rab-34
UniProt Protein Name:Ras-related protein Rab-34, isoform NARR
UniProt Synonym Protein Names:Nine amino-acid residue-repeats
Protein Family:Ras-related protein
UniProt Gene Name:RAB34  

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