RAB34 Antibody (PACO06785)
- SKU:
- PACO06785
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
RAB34 Antibody (PACO06785)
The Rab34 Polyclonal Antibody (PACO06785) is a valuable tool for researchers studying Rab34, a small GTPase protein involved in intracellular vesicle trafficking. This antibody, produced in rabbits, has high reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to Rab34 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and molecular biology.Rab34 is known to regulate various cellular processes, such as endocytic pathway, autophagy, and cytokinesis. Its role in these pathways makes it a promising target for research in diseases related to vesicle trafficking and intracellular transport.
By studying Rab34 activity, researchers can gain insights into the mechanisms underlying cellular functions and potential therapeutic targets for diseases like neurodegenerative disorders and infectious diseases.Overall, the Rab34 Polyclonal Antibody is a powerful tool for investigating the roles of Rab34 in cellular processes and disease mechanisms. Its high specificity and reactivity make it a reliable choice for researchers looking to further understand the intricate functions of Rab34 in cellular biology.
| Antibody Name: | RAB34 Antibody (PACO06785) |
| Antibody SKU: | PACO06785 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human Rab 34. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of 293T lysis using Rab 34 antibody. |
 | Western Blot analysis of 293 cells using Rab 34 Polyclonal Antibody. |
| Synonyms: | RAB34; RAB39; RAH; Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah |
| UniProt Protein Function: | RAB34: Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: Golgi apparatus; Golgi cisterna; Golgi stack; perinuclear region of cytoplasm; phagocytic vesicle; phagocytic vesicle membrane; vesicle Molecular Function:GTP binding; protein binding; Ral GTPase binding Biological Process: antigen processing and presentation; Golgi to plasma membrane protein transport; lysosome localization; small GTPase mediated signal transduction |
| NCBI Summary: | This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012] |
| UniProt Code: | Q9BZG1 |
| NCBI GenInfo Identifier: | 20139693 |
| NCBI Gene ID: | 83871 |
| NCBI Accession: | Q9BZG1.1 |
| UniProt Secondary Accession: | Q9BZG1,Q5BJE6, Q8NCJ8, Q96AR4, B4E3A0, E9PEJ9, |
| UniProt Related Accession: | Q9BZG1 |
| Molecular Weight: | 21,118 Da |
| NCBI Full Name: | Ras-related protein Rab-34 |
| NCBI Synonym Full Names: | RAB34, member RAS oncogene family |
| NCBI Official Symbol: | RAB34Â Â |
| NCBI Official Synonym Symbols: | RAH; RAB39Â Â |
| NCBI Protein Information: | ras-related protein Rab-34 |
| UniProt Protein Name: | Ras-related protein Rab-34 |
| UniProt Synonym Protein Names: | Ras-related protein Rab-39; Ras-related protein Rah |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB34Â Â |
| UniProt Entry Name: | RAB34_HUMAN |
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