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RAB32 Antibody (PACO11648)

SKU:
PACO11648
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459

Description

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RAB32 Antibody (PACO11648)

The Rab32 Polyclonal Antibody (PAC011648) is a valuable tool for researchers studying Rab32, a small GTPase involved in intracellular vesicle trafficking. This antibody, generated in rabbits, shows high reactivity with human, mouse, and rat samples, making it versatile for a range of experimental settings.Rab32 is known to play a role in various cellular processes, including organelle dynamics, autophagy, and membrane trafficking. Its dysfunction has been implicated in diseases such as neurodegenerative disorders and cancer. By using the Rab32 antibody in techniques such as Western blot and immunofluorescence, researchers can detect and study Rab32 expression and localization in different cell types and tissues.

Understanding the function of Rab32 is essential for uncovering its involvement in physiological and pathological processes. With its specificity and sensitivity, the Rab32 Polyclonal Antibody is a valuable tool for elucidating the mechanisms underlying Rab32-mediated cellular functions and the potential implications for disease development and progression.

Antibody Name:RAB32 Antibody (PACO11648)
Antibody SKU:PACO11648
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human RAB32
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:RAB32, member RAS oncogene family;
UniProt Protein Function:RAB32: Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Belongs to the small GTPase superfamily. Rab family.
UniProt Protein Details:

Protein type:G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 6q24.3

Cellular Component: early endosome; melanosome; membrane; mitochondrion; phagocytic vesicle; trans-Golgi network

Molecular Function:GTP-dependent protein binding; GTPase activity; protein binding

Biological Process: antigen processing and presentation

NCBI Summary:The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. [provided by RefSeq, Dec 2015]
UniProt Code:Q13637
NCBI GenInfo Identifier:2833245
NCBI Gene ID:10981
NCBI Accession:Q13637.3
UniProt Related Accession:Q13637
Molecular Weight:24,997 Da
NCBI Full Name:Ras-related protein Rab-32
NCBI Synonym Full Names:RAB32, member RAS oncogene family
NCBI Official Symbol:RAB32  
NCBI Protein Information:ras-related protein Rab-32
UniProt Protein Name:Ras-related protein Rab-32
Protein Family:Ras-related protein
UniProt Gene Name:RAB32  
UniProt Entry Name:RAB32_HUMAN

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