The Rab31 Polyclonal Antibody (CAB7506) is a valuable tool for researchers studying the Rab31 protein, a member of the Ras superfamily of small GTPases involved in intracellular vesicle trafficking. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to Rab31, this antibody enables the detection and analysis of the protein in various cell types, making it ideal for investigations in cell biology and molecular biology research.Rab31 plays a critical role in regulating membrane traffic and protein transport within cells, making it a key player in processes such as endocytosis, autophagy, and vesicle formation.
Dysregulation of Rab31 has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases. Therefore, understanding the function and regulation of Rab31 is essential for exploring its potential as a therapeutic target in these pathological conditions.Overall, the Rab31 Polyclonal Antibody offers researchers a reliable tool for studying the function of Rab31 in various cellular processes and disease states, paving the way for new insights and potential therapeutic strategies.
Product Name:
RAB31 Rabbit Polyclonal Antibody
SKU:
CAB7506
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human RAB31 (NP_006859.2).
Enables GDP binding activity and GTP binding activity. Involved in several processes, including Golgi to plasma membrane protein transport; cellular response to insulin stimulus; and receptor internalization. Located in early endosome; phagocytic vesicle; and trans-Golgi network membrane. Biomarker of severe acute respiratory syndrome.
Purification Method:
Affinity purification
Gene ID:
11031
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB31 antibody (CAB7506) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
