The Rab2B Polyclonal Antibody (PAC022553) is a valuable tool for researchers studying Rab2B, a member of the Rab family of small GTPases known to play crucial roles in cellular transport and membrane trafficking. This antibody, produced in rabbits, is highly specific to human Rab2B protein and has been validated for use in Western blot applications.Rab2B is involved in regulating vesicular transport between the endoplasmic reticulum and the Golgi apparatus, making it essential for maintaining proper cellular function.
Research on Rab2B has implications for understanding various cellular processes, including protein sorting, organelle organization, and secretion pathways.By utilizing the Rab2B Polyclonal Antibody, researchers can study the localization, expression levels, and function of Rab2B in different cell types and experimental conditions. This antibody provides a reliable tool for investigating the role of Rab2B in cellular processes and its potential involvement in diseases related to membrane trafficking dysfunction.
Antibody Name:
RAB2B Antibody (PACO22553)
Antibody SKU:
PACO22553
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human RAB2B.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, HeLa cells and 293 cells, using RAB2B antibody.
Background:
Required for protein transport from the endoplasmic reticulum to the Golgi complex Potential.
Synonyms:
Ras-related protein Rab-2B;
UniProt Protein Function:
RAB2B: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential). Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric; G protein; G protein, monomeric, RabChromosomal Location of Human Ortholog: 14q11.2Molecular Function: protein bindingBiological Process: positive regulation of exocytosis
UniProt Protein Details:
NCBI Summary:
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
