The Rab2B Polyclonal Antibody (PACO05546) is a vital tool for researchers studying Rab2B, a small GTPase protein involved in intracellular vesicle trafficking. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications. By binding specifically to Rab2B, researchers can accurately detect and analyze its expression in various cell types, facilitating investigations in cellular biology and molecular biology.Rab2B is a key regulator of vesicle transport between the endoplasmic reticulum and Golgi apparatus, playing a crucial role in maintaining cellular homeostasis.
Dysregulation of Rab2B has been associated with various diseases, including neurodegenerative disorders and cancer. By elucidating the functions and pathways involving Rab2B, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets for treatment.Overall, the Rab2B Polyclonal Antibody (PACO05546) offers researchers a reliable tool to study the role of Rab2B in cellular processes and disease pathogenesis, paving the way for advancements in biomedical research and drug discovery.
Antibody Name:
RAB2B Antibody (PACO05546)
Antibody SKU:
PACO05546
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the Internal region of human Rab 2B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RAB2B; Ras-related protein Rab-2B
UniProt Protein Function:
RAB2B: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential). Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric; G protein; G protein, monomeric, RabChromosomal Location of Human Ortholog: 14q11.2Molecular Function: protein bindingBiological Process: positive regulation of exocytosis
UniProt Protein Details:
NCBI Summary:
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
